|
|
(-)-limonene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (-)-trans-isopiperitenol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
M
|
|
MetaCyc:
--LIMONENE-3-MONOOXYGENASE-RXN
|
|
|
|
(-)-limonene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (-)-trans-carveol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.51
(S)-limonene 6-monooxygenase
|
–
|
M
|
|
MetaCyc:
--LIMONENE-6-MONOOXYGENASE-RXN
|
|
|
|
(-)-limonene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-perillyl_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.52
(S)-limonene 7-monooxygenase
|
–
|
M
|
|
MetaCyc:
--LIMONENE-7-MONOOXYGENASE-RXN
|
|
|
|
(S)-cheilanthifoline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-Stylopine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.64
(S)-stylopine synthase
|
–
|
M
|
|
MetaCyc:
1.1.3.32-RXN
|
|
|
|
(R)-N-methylcoclaurine + (S)-N-methylcoclaurine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Berbamunine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.66
berbamunine synthase
|
–
|
M
|
|
MetaCyc:
1.1.3.34-RXN
|
|
|
|
(R)-reticuline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> salutaridine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.67
salutaridine synthase
|
–
|
M
|
|
MetaCyc:
1.1.3.35-RXN
|
|
|
|
(S)-tetrahydrocolumbamine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-canadine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.68
(S)-canadine synthase
|
–
|
M
|
|
MetaCyc:
1.1.3.36-RXN
|
|
|
|
sophoraflavanone_B + reduced_[NADPH-hemoprotein_reductase] + O2 <=> leachianone_G + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.142
8-dimethylallylnaringenin 2'-hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.13.103-RXN
|
|
|
|
(R)-pulegone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-menthofuran + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.143
(+)-menthofuran synthase
|
–
|
M
|
|
MetaCyc:
1.14.13.104-RXN
|
|
|
|
L-isoleucine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (1E,2S)-2-methylbutanal_oxime + oxidized_[NADPH-hemoprotein_reductase] + CO2 + H2O
|
1.14.14.39
isoleucine N-monooxygenase
|
–
|
|
|
MetaCyc:
1.14.13.117-RXN
|
|
|
|
L-valine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (E)-2-methylpropanal-oxime + oxidized_[NADPH-hemoprotein_reductase] + CO2 + H2O
|
1.14.14.38
valine N-monooxygenase
|
–
|
|
|
MetaCyc:
1.14.13.118-RXN
|
|
|
|
5-O-p-coumaroylquinic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> chlorogenic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.36-RXN
|
|
|
|
(S)-N-methylcanadine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Allocryptopine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.37-RXN
|
|
|
|
4-Hydroxyphenylacetonitrile + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-4-hydroxymandelonitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.13.42
hydroxyphenylacetonitrile 2-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.42-RXN
|
|
|
|
protopine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-hydroxyprotopine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.98
protopine 6-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.55-RXN
|
|
|
|
Dihydrosanguinarine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 10-Hydroxydihydrosanguinarine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.100
dihydrosanguinarine 10-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.56-RXN
|
|
|
|
dihydrochelirubine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 12-hydroxydihydrochelirubine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.101
dihydrochelirubine 12-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.57-RXN
|
|
|
|
Quinine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3-hydroxyquinine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.55
quinine 3-monooxygenase
|
–
|
|
|
MetaCyc:
1.14.13.67-RXN
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-4-hydroxymandelonitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
|
|
MetaCyc:
1.14.13.68-RXN
|
|
|
|
obtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
1.14.13.70-RXN
|
|
|
|
(S)-N-methylcoclaurine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-3''-hydroxy-N-methylcoclaurine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.102
N-methylcoclaurine 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
1.14.13.71-RXN
|
|
|
|
tabersonine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 16-hydroxytabersonine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.103
tabersonine 16-hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.13.73-RXN
|
|
|
|
7-deoxyloganin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> loganin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
|
|
MetaCyc:
1.14.13.74-RXN
|
|
|
|
vinorine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 21-epi-vomilenine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.104
vinorine hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.13.75-RXN
|
|
|
|
taxa-4(20),11-dien-5alpha-yl_acetate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.105
taxane 10beta-hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.13.76-RXN
|
|
|
|
taxa-4(20),11-dien-5alpha-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> taxa-4(20),11-dien-5alpha,13alpha-diol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.106
taxane 13alpha-hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.13.77-RXN
|
|
|
|
ent-kaurene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-kaur-16-en-19-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.13.78
ent-kaurene oxidase
|
–
|
M
|
|
MetaCyc:
1.14.13.78-RXN
|
|
|
|
ent-kaur-16-en-19-oate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-7alpha-hydroxykaur-16-en-19-oate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.13.79
ent-kaurenoic acid oxidase
|
–
|
M
|
|
MetaCyc:
1.14.13.79-RXN
|
|
|
|
10-deoxysarpagine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> sarpagine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.136
deoxysarpagine hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.13.91-RXN
|
|
|
|
abscisic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 8''-hydroxyabscisate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.eo
|
–
|
M
|
|
MetaCyc:
1.14.13.93-RXN
|
|
|
|
lithocholic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6beta-hydroxylithocholate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.138
lithocholate 6beta-hydroxylase
|
–
|
|
|
MetaCyc:
1.14.13.94-RXN
|
|
|
|
5beta-cholestane-3alpha,7alpha-diol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5beta-cholestane-3alpha,7alpha,12alpha-triol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.139
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
|
–
|
|
|
MetaCyc:
1.14.13.96-RXN
|
|
|
|
cholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (24S)-24-hydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
MetaCyc:
1.14.13.98-RXN
|
|
|
|
(24S)-24-hydroxycholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (24S)-cholest-5-ene-3beta,7alpha,24-triol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.26
24-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
MetaCyc:
1.14.13.99-RXN
|
|
|
|
(S)-scoulerine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-cheilanthifoline + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.65
(S)-cheilanthifoline synthase
|
–
|
M
|
|
MetaCyc:
1.14.21.2-RXN
|
|
|
|
taxa-4,11-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> taxa-4(20),11-dien-5alpha-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.176
taxadiene 5alpha-hydroxylase
|
–
|
M
|
|
MetaCyc:
1.14.99.37-RXN
|
|
|
|
loganin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> secologanin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.62
secologanin synthase
|
–
|
M
|
|
MetaCyc:
1.3.3.9-RXN
|
|
|
|
17alpha-hydroxyprogesterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4-androstene-3,17-dione + acetate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
|
|
MetaCyc:
4.1.2.30-RXN
|
|
|
|
benzoate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4-hydroxybenzoate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.92
benzoate 4-monooxygenase
|
–
|
|
|
MetaCyc:
BENZOATE-4-MONOOXYGENASE-RXN
|
|
|
|
cholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7alpha-hydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
M
|
|
MetaCyc:
CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN
|
|
|
|
flavonoids + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3''-hydroxy-flavonoid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
MetaCyc:
FLAVONOID-3-MONOOXYGENASE-RXN
|
|
|
|
heme + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> Biliverdin + Fe2+ + CO + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
|
–
|
M
|
|
MetaCyc:
HEME-OXYGENASE-DECYCLIZING-RXN
|
|
|
|
formononetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2'-hydroxyformononetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
|
–
|
M
|
|
MetaCyc:
ISOFLAVONE-2-HYDROXYLASE-RXN
|
|
|
|
leukotriene_B4 + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 20-hydroxy-leukotriene_B4 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
MetaCyc:
LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN
|
|
|
|
linalool + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (6E)-8-hydroxylinalool + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
LINALOOL-8-MONOOXYGENASE-RXN
|
|
|
|
geranylgeraniol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 18-hydroxygeranylgeraniol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.146
geranylgeraniol 18-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-10626
|
|
|
|
alpha-humulene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 10-hydroxy-alpha-humulene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.113
alpha-humulene 10-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-10628
|
|
|
|
oleoyl-CoA + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 18-hydroxyoleoyl-CoA + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-1063
|
|
|
|
(+)-limonene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-trans-carveol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.53
(R)-limonene 6-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-10746
|
|
|
|
alpha-tocopherol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 13''-hydroxy-alpha-tocopherol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-11003
|
|
|
|
p-coumaric_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> caffeic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-1103
|
|
|
|
6-deoxocathasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-deoxotyphasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-11052
|
|
|
|
Melatonin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6-hydroxymelatonin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-11056
|
|
|
|
Melatonin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N-acetylserotonin + oxidized_[NADPH-hemoprotein_reductase] + formaldehyde + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-11057
|
|
|
|
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3-dehydro-6-deoxoteasterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-11101
|
|
|
|
ferulic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5-hydroxyferulic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-1121
|
|
|
|
N1,N5,N10-Tricoumaroyl_spermidine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N1,N5,N10-Tricaffeoyl_spermidine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11260
|
|
|
|
N1,N5,N10-Triferuloyl_spermidine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N1,N5,N10-Tri(hydroxyferuloyl)_spermidine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11262
|
|
|
|
benzoate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> salicylate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-11271
|
|
|
|
Decanoate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 10-Hydroxydecanoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M34
|
–
|
|
|
MetaCyc:
RXN-11325
|
|
|
|
laurate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 12-hydroxydodecanoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M34
|
–
|
|
|
MetaCyc:
RXN-11336
|
|
|
|
laurate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-hydroxylauric_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-11340
|
|
|
|
gibberellin_a4 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 16alpha,17-epoxy_GA4 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11385
|
|
|
|
gibberellin_A12 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 16alpha,17-epoxy_GA12 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11387
|
|
|
|
gibberellin_a9 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 16alpha,17-epoxy_GA9 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11388
|
|
|
|
(E)-phenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-aci-nitro-2-phenylethane + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11412
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 1-aci-nitro-2-indolyl-ethane + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11413
|
|
|
|
(E)-4-(methylsulfanyl)butanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_1-aci-nitro-omega-(methylthio)alkane + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11414
|
|
|
|
(E)-5-(methylsulfanyl)pentanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_1-aci-nitro-omega-(methylthio)alkane + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11415
|
|
|
|
6-Methylthiohexanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-(methylsulfanyl)-6-aci-nitrohexane + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11416
|
|
|
|
4-methylthioheptanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-(methylsulfanyl)-7-aci-nitroheptane + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11417
|
|
|
|
4-methylthiooctanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-(methylsulfanyl)-8-aci-nitrooctane + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11418
|
|
|
|
4-methylthiononanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-(methylsulfanyl)-9-aci-nitrononane + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11419
|
|
|
|
coniferyl_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5-hydroxyconiferaldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-1142
|
|
|
|
coniferyl_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5-hydroxyconiferyl_alcohol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-1144
|
|
|
|
(22S)-22-hydroxycampesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11529
|
|
|
|
(22S)-22-hydroxycampest-4-en-3-one + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (22R,23R)-22,23-dihydroxycampest-4-en-3-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11530
|
|
|
|
3-epi-6-deoxocathasterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6-deoxotyphasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11531
|
|
|
|
3-dehydro-6-deoxoteasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3-dehydro-6-hydroxyteasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11535
|
|
|
|
6-deoxoteasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-hydroxyteasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11536
|
|
|
|
Teasterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7-Oxateasterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11537
|
|
|
|
typhasterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7-Oxatyphasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11538
|
|
|
|
24-epicastasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 26-Hydroxycastasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11540
|
|
|
|
Pratensein + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5-hydroxypseudobaptigenin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.63
pseudobaptigenin synthase
|
–
|
|
|
MetaCyc:
RXN-11547
|
|
|
|
methyl_farnesoate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> juvenile_hormone_III + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.127
methyl farnesoate epoxidase
|
–
|
M
|
|
MetaCyc:
RXN-11621
|
|
|
|
(S)-dihydrodaidzein + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (3R)-2''-hydroxydihydrodaidzein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-11641
|
|
|
|
2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (R)-dihydrocamalexate + cyanide + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11666
|
|
|
|
1-palmitoyl-2-linoleoylphosphatidylcholine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M33
|
–
|
M
|
|
MetaCyc:
RXN-11671
|
|
|
|
farnesoic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> juvenile_hormone_III_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.128
farnesoate epoxidase
|
–
|
M
|
|
MetaCyc:
RXN-11770
|
|
|
|
isoflavone + reduced_[NADPH-hemoprotein_reductase] + H+ + O2 <=> 2''-hydroxyisoflavone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-11846
|
|
|
|
N-debenzoyl-(3''-RS)-2''-deoxytaxol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N-debenzoyl-(3''-RS)-taxol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-11851
|
|
|
|
Zymosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-11881
|
|
|
|
solavetivol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> solavetivone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11907
|
|
|
|
5-epiaristolochene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> capsidiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
|
|
MetaCyc:
RXN-11908
|
|
|
|
(3S,6E)-nerolidol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (3E)-4,8-dimethylnona-1,3,7-triene + 3-buten-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.59
dimethylnonatriene synthase
|
–
|
M
|
|
MetaCyc:
RXN-11911
|
|
|
|
L-tryptophan + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-tryptophan + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12061
|
|
|
|
N-hydroxy-L-tryptophan + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxy-L-tryptophan + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12062
|
|
|
|
L-phenylalanine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-phenylalanine + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12066
|
|
|
|
N-hydroxy-L-phenylalanine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxy-L-phenylalanine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12067
|
|
|
|
(9Z)-12,13-epoxyoctadec-9-enoate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 9,10-12,13-diepoxy-octadecanoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M33
|
–
|
M
|
|
MetaCyc:
RXN-12136
|
|
|
|
linolenic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (12Z,15Z)-9,10-epoxyoctadeca-12,15-dienoic_aicd + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M33
|
–
|
M
|
|
MetaCyc:
RXN-12137
|
|
|
|
linolenic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (9Z,15Z)-12,13-epoxy-octadeca-9,15-dienoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M33
|
–
|
M
|
|
MetaCyc:
RXN-12138
|
|
|
|
linolenic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (9Z,12Z)-15,16-epoxyoctadeca-9,12-dienoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M33
|
–
|
M
|
|
MetaCyc:
RXN-12139
|
|
|
|
oleic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> trans-9,10-epoxystearate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M33
|
–
|
M
|
|
MetaCyc:
RXN-12143
|
|
|
|
behenoyl-CoA + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 22-hydroxy-docosanoyl-CoA + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-12155
|
|
|
|
laurate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7-hydroxydodecanoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.130
laurate 7-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-12186
|
|
|
|
alpha-carotene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> alpha-cryptoxanthin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
|
|
MetaCyc:
RXN-12226
|
|
|
|
artemisinic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> artemisinate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12314
|
|
|
|
(+)-7-epi-jasmonoyl-L-isoleucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-hydroxyjasmonoyl-L-isoleucine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-12421
|
|
|
|
justicidin_B + reduced_[NADPH-hemoprotein_reductase] + O2 <=> diphyllin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-12441
|
|
|
|
phenylacetate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-hydroxyphenylacetate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.54
phenylacetate 2-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-12489
|
|
|
|
kaempferol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> quercetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-12510
|
|
|
|
(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> zealexin_A1 + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12605
|
|
|
|
(S)-beta-macrocarpene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]_methanol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12656
|
|
|
|
[(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]_methanol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12657
|
|
|
|
beta-amyrin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 11-oxo-beta-amyrin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
MetaCyc:
RXN-12680
|
|
|
|
beta-amyrin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 11alpha-hydroxy-beta-amyrin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12681
|
|
|
|
11alpha-hydroxy-beta-amyrin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 11-oxo-beta-amyrin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12682
|
|
|
|
30-hydroxy-beta-amyrin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-12683
|
|
|
|
abietadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> abietic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
MetaCyc:
RXN-12799
|
|
|
|
ent-isokaurene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-isokauren-2beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-12879
|
|
|
|
9beta-pimara-7,15-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 9beta-pimara-7,15-dien-19-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12880
|
|
|
|
9beta-pimara-7,15-dien-19-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 9beta-pimara-7,15-dien-19-al + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12881
|
|
|
|
9beta-pimara-7,15-dien-19-al + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 9beta-pimara-7,15-dien-19-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12882
|
|
|
|
9beta-pimara-7,15-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 9beta-pimara-7,15-dien-19-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
MetaCyc:
RXN-12883
|
|
|
|
ent-cassa-12,15-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-11beta-hydroxycassa-12,15-diene + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.112
ent-cassa-12,15-diene 11-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-12884
|
|
|
|
taxusin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 7beta-hydroxytaxusin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13.147
taxoid 7beta-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-12885
|
|
|
|
(6E)-8-hydroxylinalool + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (6E)-8-oxolinalool + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-12966
|
|
|
|
linalool + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (6E)-8-oxolinalool + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-12967
|
|
|
|
L-tetrahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-tetrahomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-12989
|
|
|
|
N-hydroxyhexahomomethioniate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxyhexahomomethioniate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-12990
|
|
|
|
L-pentahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxypentahomomethionine + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13003
|
|
|
|
N-hydroxypentahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxypentahomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13004
|
|
|
|
L-homomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> an_L-N-hydroxypolyhomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13014
|
|
|
|
an_L-N-hydroxypolyhomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> an_L-N,N-dihydroxypolyhomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13015
|
|
|
|
L-dihomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-dihomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13017
|
|
|
|
N-hydroxy-L-dihomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxy-L-dihomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13019
|
|
|
|
L-trihomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxytrihomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13021
|
|
|
|
N-hydroxytrihomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,_N-dihydroxytrihomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13022
|
|
|
|
N-hydroxy-tetrahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,_N-dihydroxy-tetrahomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13024
|
|
|
|
L-hexahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxyhexahomomethioniate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13027
|
|
|
|
1,5-anhydro-D-mannitol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> D-mannose + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-13064
|
|
|
|
L-tyrosine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> p-hydroxyphenylacetaldoxime + oxidized_[NADPH-hemoprotein_reductase] + CO2 + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13187
|
|
|
|
ent-kaur-16-en-19-oate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> gibberellin_A12 + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13189
|
|
|
|
ent-kaurene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-kaur-16-en-19-oate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13190
|
|
|
|
flavanone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3,5''-dihydroxy_isoflavanone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-13192
|
|
|
|
7-dehydrocholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7-oxocholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13220
|
|
|
|
(15Z)-tetracos-15-enal + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (9Z)-tricosene + CO2 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-13288
|
|
|
|
(-)-vetispiradiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> solavetivone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
|
MetaCyc:
RXN-13397
|
|
|
|
amorpha-4,11-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13432
|
|
|
|
taxusin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2alpha-hydroxytaxusin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-13486
|
|
|
|
7beta-hydroxytaxusin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2alpha,_7beta-dihydroxytaxusin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-13487
|
|
|
|
2alpha-hydroxytaxusin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2alpha,_7beta-dihydroxytaxusin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13.147
taxoid 7beta-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-13488
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 30-hydroxy-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13489
|
|
|
|
11alpha,30-dihydroxy-beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 30-hydroxy-11-oxo-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-13491
|
|
|
|
11-oxo-beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 30-hydroxy-11-oxo-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13492
|
|
|
|
30-hydroxy-11-oxo-beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> glycyrrhetaldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13493
|
|
|
|
glycyrrhetaldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> glycyrrhetinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13494
|
|
|
|
lupeol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> betulin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13497
|
|
|
|
betulin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> betulinic_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13498
|
|
|
|
betulinic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> betulinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13499
|
|
|
|
alpha-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> uvaol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13500
|
|
|
|
uvaol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ursolic_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13501
|
|
|
|
ursolic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ursolic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13502
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> erythrodiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13503
|
|
|
|
erythrodiol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oleanolic_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13504
|
|
|
|
oleanolic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oleanolic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13505
|
|
|
|
11-oxo-beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> glycyrrhetinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
MetaCyc:
RXN-13506
|
|
|
|
lupeol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> betulinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13507
|
|
|
|
alpha-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ursolic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13508
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oleanolic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.126
beta-amyrin 28-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-13509
|
|
|
|
4-Hydroxyphenylacetonitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (R)-4-hydroxymandelonitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13622
|
|
|
|
24,25-dihydrolanosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-13707
|
|
|
|
naringenin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (2S)-dihydrotricetin + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-13717
|
|
|
|
taxifolin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> dihydromyricetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13718
|
|
|
|
(S)-N-methylcanadine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-1-hydroxy-N-methylcanadine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.166
(S)-N-methylcanadine 1-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-13807
|
|
|
|
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.167
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-13808
|
|
|
|
Allocryptopine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6-hydroxyallocryptopine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-13828
|
|
|
|
quercetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> quercetagetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-13898
|
|
|
|
a_14alpha-methylsteroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_DELTA14-steroid + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-13961
|
|
|
|
L-tryptophan + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (E,Z)-indolyl-3-acetaldoxime + oxidized_[NADPH-hemoprotein_reductase] + H2O + CO2
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-1402
|
|
|
|
strictosamide_ketolactam + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Pumiloside + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-14030
|
|
|
|
naringenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-hydroxynaringenin + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-14069
|
|
|
|
eriodictyol + reduced_[NADPH-hemoprotein_reductase] + O2 + H+ <=> 2-hydroxyeriodictyol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-14077
|
|
|
|
pinocembrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2,5,7-trihydroxyflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-14083
|
|
|
|
(1E,2S)-2-methylbutanal_oxime + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-Methyl-2-hydroxybutyronitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
|
MetaCyc:
RXN-14132
|
|
|
|
tryprostatin_B + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6-hydroxytryprostatin_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.118
tryprostatin B 6-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-14413
|
|
|
|
fumitremorgin_C + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 12alpha,13alpha-dihydroxyfumitremorgin_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.119
fumitremorgin C monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-14414
|
|
|
|
tryprostatin_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> fumitremorgin_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
M
|
|
MetaCyc:
RXN-14415
|
|
|
|
tryprostatin_B + reduced_[NADPH-hemoprotein_reductase] + O2 <=> demethoxyfumitremorgin_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
M
|
|
MetaCyc:
RXN-14416
|
|
|
|
2,22,25-trideoxyecdysone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2,22-dideoxyecdysone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-14677
|
|
|
|
20-hydroxyecdysone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20-hydroxyecdysonate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-14736
|
|
|
|
20-hydroxyecdysone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20,26-Dihydroxyecdysone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14737
|
|
|
|
20,26-Dihydroxyecdysone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20-hydroxyecdysone-26-aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14738
|
|
|
|
20-hydroxyecdysone-26-aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20-hydroxyecdysonate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14739
|
|
|
|
testosterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 17beta-estradiol + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
1.14.14.14
aromatase
|
–
|
|
|
MetaCyc:
RXN-14744
|
|
|
|
4-androstene-3,17-dione + reduced_[NADPH-hemoprotein_reductase] + O2 <=> estrone + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
1.14.14.14
aromatase
|
–
|
|
|
MetaCyc:
RXN-14746
|
|
|
|
genkwanin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> scutellarein-7-methyl_ether + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-14748
|
|
|
|
apigenin-7,4''-dimethyl_ether + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ladanein + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-14751
|
|
|
|
sakuranetin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> carthamidin-7-methyl_ether + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-14754
|
|
|
|
(S)-Coclaurine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-6-O-methylnorlaudanosoline + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-14879
|
|
|
|
(20S)-dammarenediol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> protopanaxadiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.120
dammarenediol 12-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-14975
|
|
|
|
protopanaxadiol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> protopanaxatriol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.121
protopanaxadiol 6-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-14978
|
|
|
|
myrcene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (4S)-(+)-ipsdienol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.31
ipsdienol synthase
|
–
|
M
|
|
MetaCyc:
RXN-15039
|
|
|
|
myrcene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (4R)-ipsdienol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.31
ipsdienol synthase
|
–
|
M
|
|
MetaCyc:
RXN-15040
|
|
|
|
iridotrial + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 7-deoxyloganetate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15237
|
|
|
|
octadecanal + reduced_[NADPH-hemoprotein_reductase] + O2 <=> heptadecane + oxidized_[NADPH-hemoprotein_reductase] + CO2 + H2O
|
4.1.99
|
–
|
|
|
MetaCyc:
RXN-15324
|
|
|
|
ent-sandaracopimara-8(14),15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-sandaracopimaradien-3beta-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.70
ent-sandaracopimaradiene 3-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-15379
|
|
|
|
ent-sandaracopimaradien-3beta-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oryzalexin_E + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.122
oryzalexin E synthase
|
–
|
M
|
|
MetaCyc:
RXN-15381
|
|
|
|
ent-sandaracopimaradien-3beta-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oryzalexin_D + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.123
oryzalexin D synthase
|
–
|
M
|
|
MetaCyc:
RXN-15382
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 12,13beta-epoxy-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15383
|
|
|
|
12,13beta-epoxy-beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15384
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> maniladiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.63
beta-amyrin 16beta-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-15385
|
|
|
|
maniladiol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15386
|
|
|
|
ent-sandaracopimara-8(14),15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7beta-hydroxy-ent-sandaracopimaradiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15394
|
|
|
|
vitamin_K + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-hydroxyphylloquinone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15395
|
|
|
|
naringenin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 2,5,7,4'-tetrahydroxyisoflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
M
|
|
MetaCyc:
RXN-1541
|
|
|
|
ent-3beta-hydroxy-cassa-12,15-diene-11-one + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-cassa-12,15-diene-2beta,3beta-diol-11-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15433
|
|
|
|
stemod-13(17)-ene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> syn-stemoden-19-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
M
|
|
MetaCyc:
RXN-15437
|
|
|
|
stemod-13(17)-ene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> syn-stemoden-19-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15438
|
|
|
|
syn-stemoden-19-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> syn-stemoden-19-al + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15439
|
|
|
|
syn-stemoden-19-al + reduced_[NADPH-hemoprotein_reductase] + O2 <=> syn-stemoden-19-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15440
|
|
|
|
7beta-hydroxy-ent-sandaracopimaradiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oryzalexin_D + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15441
|
|
|
|
ent-cassa-12,15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3alpha-hydroxy-ent-cassadiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15444
|
|
|
|
3alpha-hydroxy-ent-cassadiene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-3beta-hydroxy-cassa-12,15-diene-11-one + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15445
|
|
|
|
9beta-pimara-7,15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6beta-hydroxy-syn-pimaradiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15452
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15458
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.168
germacrene A acid 8beta-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-15460
|
|
|
|
ent-cassa-12,15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2alpha-hydroxy-ent-cassadiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15462
|
|
|
|
ent-3beta-hydroxycassa-12,15-dien-2-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-cassa-12,15-diene-2beta,3beta-diol-11-one + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15463
|
|
|
|
m-cresol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3-Hydroxybenzyl_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15470
|
|
|
|
m-cresol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> toluquinol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-15472
|
|
|
|
3-Hydroxybenzyl_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> gentisyl_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15473
|
|
|
|
Paspaline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> beta-PC-M6 + formate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15499
|
|
|
|
beta-PC-M6 + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 13-Desoxypaxilline + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15500
|
|
|
|
13-Desoxypaxilline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Paxilline + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15501
|
|
|
|
(+)-costunolide + reduced_[NADPH-hemoprotein_reductase] + O2 <=> parthenolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15531
|
|
|
|
parthenolide + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3beta-hydroxyparthenolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15532
|
|
|
|
(+)-costunolide + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3beta-hydroxycostunolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15533
|
|
|
|
(S)-scoulerine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-nandinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.73
(S)-nandinine synthase
|
–
|
M
|
|
MetaCyc:
RXN-15538
|
|
|
|
fusicocca-2,10(14)-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> fusicocca-2,10(14)-diene-8beta-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15591
|
|
|
|
fusicocca-2,10(14)-diene-8beta-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> fusicocca-2,10(14)-diene-8beta,16-diol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15592
|
|
|
|
dihydromonacolin_L_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3alpha-hydroxy-3,5-dihydromonacolin_L_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15671
|
|
|
|
dihydromonacolin_L_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> monacolin_L_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.124
dihydromonacolin L hydroxylase
|
–
|
|
|
MetaCyc:
RXN-15673
|
|
|
|
monacolin_L_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> monacolin_J_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.125
monacolin L hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-15674
|
|
|
|
docosahexaenoic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 22-hydroxydocosahexaenoic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-15675
|
|
|
|
cyclo(L-phenylalanyl-L-seryl) + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15679
|
|
|
|
Paspaline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Terpendole_E + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15735
|
|
|
|
13-Desoxypaxilline + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Paspalicine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-15737
|
|
|
|
Paspalicine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Paspalinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15738
|
|
|
|
Fumiquinazoline_F + reduced_[NADPH-hemoprotein_reductase] + O2 <=> fumiquinazoline_F-indoline-2,3''-diol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15747
|
|
|
|
alpha-cyclopiazonate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-oxocyclopiazonate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15836
|
|
|
|
pretenellin_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> pretenellin_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-15886
|
|
|
|
pretenellin_B + reduced_[NADPH-hemoprotein_reductase] + O2 <=> tenellin + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15887
|
|
|
|
preaspyridone_A + O2 + reduced_[NADPH-hemoprotein_reductase] <=> aspyridone_A + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-15919
|
|
|
|
preaspyridone_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 14-hydroxypreaspyridone_A + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13
|
–
|
M
|
|
MetaCyc:
RXN-15922
|
|
|
|
Terpendole_E + reduced_[NADPH-hemoprotein_reductase] + O2 <=> terpendole_F + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15955
|
|
|
|
terpendole_F + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Terpendole_G + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15956
|
|
|
|
Terpendole_G + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Terpendole_B + oxidized_[NADPH-hemoprotein_reductase] + formate + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15957
|
|
|
|
Terpendole_B + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Terpendole_I + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15958
|
|
|
|
20,21-Diprenylterpendole_I + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Lolitriol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15960
|
|
|
|
20,21-Diprenylterpendole_J + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Lolitrem_E + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15963
|
|
|
|
Terpendole_J + reduced_[NADPH-hemoprotein_reductase] + O2 <=> terpendole_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-15965
|
|
|
|
20,21-Diprenylterpendole_C + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Lolitrem_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15967
|
|
|
|
Lolitrem_E + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Lolitrem_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-15968
|
|
|
|
linoleoyl-CoA + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 18-hydroxylinoleoyl-CoA + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.129
long-chain acyl-CoA omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-16116
|
|
|
|
Histidyltryptophyldiketopiperazine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Dehydrohistidyltryptophyldiketopiperazine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16125
|
|
|
|
Roquefortine_D + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Roquefortine_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16128
|
|
|
|
Roquefortine_C + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Glandicoline_A + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16140
|
|
|
|
Roquefortine_C + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N1-Hydroxy-roquefortine_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16141
|
|
|
|
N1-Hydroxy-roquefortine_C + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Roquefortine_L + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16142
|
|
|
|
Roquefortine_L + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Glandicoline_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16143
|
|
|
|
Glandicoline_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Glandicoline_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16144
|
|
|
|
Roquefortine_F + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Neoxaline + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16147
|
|
|
|
6-hydroxytyphasterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> typhasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16171
|
|
|
|
6-hydroxyteasterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Teasterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16172
|
|
|
|
3-dehydro-6-hydroxyteasterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3-Dehydroteasterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16173
|
|
|
|
prochaetoglobosin_I + O2 + reduced_[NADPH-hemoprotein_reductase] <=> cytoglobosin_D + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16182
|
|
|
|
cytoglobosin_D + reduced_[NADPH-hemoprotein_reductase] + O2 <=> chaetoglobosin_J + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16183
|
|
|
|
chaetoglobosin_J + O2 + reduced_[NADPH-hemoprotein_reductase] <=> chaetoglobosin_A + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16184
|
|
|
|
prochaetoglobosin_I + O2 + reduced_[NADPH-hemoprotein_reductase] <=> prochaetoglobosin_IV + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16185
|
|
|
|
prochaetoglobosin_IV + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 20-dihydro-chaetoglobosin_A + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16186
|
|
|
|
20-dihydro-chaetoglobosin_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> chaetoglobosin_A + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16187
|
|
|
|
cytoglobosin_D + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 20-dihydro-chaetoglobosin_A + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16188
|
|
|
|
(+)-pisatin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-6a-hydroxymaackiain + formaldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16217
|
|
|
|
O4,O5--dimethylthujaplicatin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (-)-yatein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16343
|
|
|
|
(-)-matairesinol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (-)-pluviatolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.72
(-)-pluviatolide synthase
|
–
|
M
|
|
MetaCyc:
RXN-16360
|
|
|
|
(-)-pluviatolide + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (-)-hinokinin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16362
|
|
|
|
fatty_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> an_omega-hydroxy-long-chain_fatty_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-16394
|
|
|
|
palmitate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 16-hydroxypalmitic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-16398
|
|
|
|
fatty_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 18-hydroxystearate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-16399
|
|
|
|
oleic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> omega-hydroxy_oleic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-16400
|
|
|
|
abscisic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 9''-hydroxyabscisate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16460
|
|
|
|
abscisic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7''-hydroxyabscisate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16465
|
|
|
|
griseophenone_C + reduced_[NADPH-hemoprotein_reductase] + O2 <=> desmethyl-dehydro-dechlorogriseofulvin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16544
|
|
|
|
previridicatumtoxin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> viridicatumtoxin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16575
|
|
|
|
abieta-8,11,13-triene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ferruginol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.175
ferruginol synthase
|
–
|
M
|
|
MetaCyc:
RXN-16786
|
|
|
|
4-coumaraldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> caffeoyl_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16806
|
|
|
|
stipitaldehyde + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1,6,8-trihydroxy-1H,3H-cyclohepta[c]furan-5-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-16828
|
|
|
|
trichodiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-hydroxytrichodiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17029
|
|
|
|
2-hydroxytrichodiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 12,13-epoxy-9,10-trichoene-2-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17030
|
|
|
|
12,13-epoxy-9,10-trichoene-2-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> isotrichodiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17031
|
|
|
|
isotrichodiol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> isotrichotriol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17032
|
|
|
|
isotrichodermin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 15-decalonectrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17036
|
|
|
|
calonectrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3,15-diacetoxyscirpenol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17038
|
|
|
|
3,4,15-triacetoxyscirpenol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3-acetylneosolaniol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17040
|
|
|
|
calonectrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7,8-dihydroxycalonectrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17043
|
|
|
|
3,4,15-triacetoxyscirpenol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7,8-dihydroxy-3,4,15-triacetoxyscirpenol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17049
|
|
|
|
3,15-acetyldeoxynivalenol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3,15-diacetylnivalenol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17051
|
|
|
|
12,13-epoxytrichothec-9-ene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> trichodermol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17057
|
|
|
|
stellata-2,6,19-triene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> stellatic_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17162
|
|
|
|
stellatic_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> stellatic_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17163
|
|
|
|
stellatic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> stellatate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17164
|
|
|
|
3-hydroxy-5-methoxybiphenyl + reduced_[NADPH-hemoprotein_reductase] + O2 <=> noraucuparin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-17182
|
|
|
|
(-)-bursehernin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (-)-5''-demethylyatein + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.131
bursehernin 5'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-17347
|
|
|
|
(-)-deoxypodophyllotoxin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (-)-4''-demethyl-deoxypodophyllotoxin + methanol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.13.M16
|
–
|
M
|
|
MetaCyc:
RXN-17349
|
|
|
|
(-)-4''-demethyl-deoxypodophyllotoxin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (-)-4''-demethyl-epipodophyllotoxin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.132
(-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-17350
|
|
|
|
Hydroxyacetone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1,1-dihydroxypropan-2-one + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17625
|
|
|
|
Hydroxyacetone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> methylglyoxal + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN-17627
|
|
|
|
indole + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3-hydroxyindole + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-17628
|
|
|
|
(E)-phenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (R)-mandelonitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18096
|
|
|
|
phenylacetonitrile + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (R)-mandelonitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-18098
|
|
|
|
(E)-2-methylpropanal-oxime + reduced_[NADPH-hemoprotein_reductase] + O2 <=> acetone_cyanohydrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18099
|
|
|
|
p-hydroxyphenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (R)-4-hydroxymandelonitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-18101
|
|
|
|
4''-O-methylnorbelladine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-Demethylnarwedine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-18123
|
|
|
|
4''-O-methylnorbelladine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (10bS,4aR)-noroxomaritidine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.50
noroxomaritidine synthase
|
–
|
M
|
|
MetaCyc:
RXN-18127
|
|
|
|
4''-O-methylnorbelladine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Noroxopluviine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-18128
|
|
|
|
(4aR,10bS)-Normaritidine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> crinine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-18134
|
|
|
|
(-)-8-Demethylmaritidine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Vittatine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-18136
|
|
|
|
Vittatine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 11-hydroxyvittatine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-18140
|
|
|
|
4''-O-methylnorbelladine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (4aS,10bR)-8-hydroxy-9-methoxy-4,4a-dihydro-3H,6H-5,10b-ethanophenanthridin-3-one + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.50
noroxomaritidine synthase
|
–
|
M
|
|
MetaCyc:
RXN-18142
|
|
|
|
(1S,15R,16S)-4-methoxy-9-azatetracyclo[7.6.1.02,7.012,16]hexadeca-2,4,6,12-tetraene-5,15-diol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Caranine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-18153
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18158
|
|
|
|
(E)-phenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> S-[(Z)-N-hydroxy(phenyl)acetimidoyl]-L-glutathione + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18159
|
|
|
|
4-methylthioheptanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)heptan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18160
|
|
|
|
(E)-4-(methylsulfanyl)butanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18161
|
|
|
|
4-methylthiononanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)nonan-1-imine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18162
|
|
|
|
4-methylthiooctanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)octan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18163
|
|
|
|
6-Methylthiohexanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)hexan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18164
|
|
|
|
(E)-5-(methylsulfanyl)pentanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)pentan-1-imine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18165
|
|
|
|
glucobrassicin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-hydroxyglucobrassicin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-18166
|
|
|
|
omega-(methylthio)-(E)-alkanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-(methylsulfanyl)-n-aci-nitroalkane + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18169
|
|
|
|
omega-(methylthio)-(E)-alkanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18171
|
|
|
|
L-homomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> an_L-N-hydroxypolyhomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18172
|
|
|
|
an_L-N-hydroxypolyhomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> an_L-N,N-dihydroxypolyhomomethionine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18173
|
|
|
|
L-homomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> omega-(methylthio)-(E)-alkanal_oxime + H2O + CO2 + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18175
|
|
|
|
2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + O2 + reduced_[NADPH-hemoprotein_reductase] <=> camalexin + cyanide + CO2 + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.52
camalexin synthase
|
–
|
|
|
MetaCyc:
RXN-18199
|
|
|
|
heme + O2 + reduced_[NADPH-hemoprotein_reductase] <=> alpha-hydroxyheme + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18341
|
|
|
|
verdoheme + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> iron(III)-biliverdine-IX_alpha + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18343
|
|
|
|
iron(III)-biliverdine-IX_alpha + reduced_[NADPH-hemoprotein_reductase] <=> Biliverdin + Fe2+ + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18344
|
|
|
|
(+)-7-epi-12-hydroxyjasmonoyl-L-isoleucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-oxojasmonoyl-L-isoleucine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18479
|
|
|
|
(+)-7-epi-12-oxojasmonoyl-L-isoleucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-hydroxy-12-oxojasmonoyl-L-isoleucine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18480
|
|
|
|
(+)-7-epi-jasmonoyl-L-phenylalanine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-hydroxyjasmonoyl-L-phenylalanine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18483
|
|
|
|
(+)-7-epi-12-hydroxyjasmonoyl-L-phenylalanine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-oxojasmonoyl-L-phenylalanine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18485
|
|
|
|
(+)-7-epi-12-oxojasmonoyl-L-phenylalanine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-hydroxy-12-oxojasmonoyl-L-phenylalanine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18486
|
|
|
|
(+)-7-epi-12-hydroxyjasmonoyl-L-isoleucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-hydroxy-12-oxojasmonoyl-L-isoleucine + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18487
|
|
|
|
(+)-7-epi-12-hydroxyjasmonoyl-L-phenylalanine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-7-epi-12-hydroxy-12-oxojasmonoyl-L-phenylalanine + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18488
|
|
|
|
a_jasmonoyl-L-amino_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> a_12-hydroxyjasmonoyl-L-amino_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.48
jasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18489
|
|
|
|
a_12-hydroxyjasmonoyl-L-amino_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> a_12-hydroxy-12-oxojasmonoyl-L-amino_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.49
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18490
|
|
|
|
a_12-hydroxyjasmonoyl-L-amino_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> a_12-oxojasmonoyl-L-amino_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18491
|
|
|
|
a_12-oxojasmonoyl-L-amino_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> a_12-hydroxy-12-oxojasmonoyl-L-amino_acid + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18492
|
|
|
|
tabersonine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.50
tabersonine 3-oxygenase
|
–
|
M
|
|
MetaCyc:
RXN-18615
|
|
|
|
16-methoxytabersonine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.50
tabersonine 3-oxygenase
|
–
|
M
|
|
MetaCyc:
RXN-18616
|
|
|
|
(S)-perillyl_alcohol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (4S)-perillyl_aldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.52
(S)-limonene 7-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-18735
|
|
|
|
p-hydroxyphenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-aci-nitro-2-(4-hydroxyphenyl)-ethane + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18756
|
|
|
|
p-hydroxyphenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> S-[(Z)-N-hydroxy(p-hydroxyphenyl)acetimidoyl]-L-glutathione + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18758
|
|
|
|
2-hydroxyphenylacetate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> homogentisate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-18767
|
|
|
|
ecdysone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20-hydroxyecdysone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.99.22
ecdysone 20-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18800
|
|
|
|
ferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-hydroxyferruginol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.60
ferruginol monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-18880
|
|
|
|
11-hydroxyferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> carnosic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.61
carnosic acid synthase
|
–
|
M
|
|
MetaCyc:
RXN-18881
|
|
|
|
ferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> salviol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.62
salviol synthase
|
–
|
|
|
MetaCyc:
RXN-18882
|
|
|
|
oleanolic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> cochalic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.63
beta-amyrin 16beta-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18883
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> daturadiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.64
beta-amyrin 6beta-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18884
|
|
|
|
ferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> sugiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.65
sugiol synthase
|
–
|
|
|
MetaCyc:
RXN-18901
|
|
|
|
11-hydroxyferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-hydroxysugiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.65
sugiol synthase
|
–
|
|
|
MetaCyc:
RXN-18902
|
|
|
|
11-hydroxysugiol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11,20-dihydroxysugiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.67
11-hydroxysugiol 20-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18903
|
|
|
|
11-hydroxyferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11,20-dihydroxyferruginol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.67
11-hydroxysugiol 20-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18904
|
|
|
|
9beta-pimara-7,15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 9beta-pimara-7,15-diene-3beta-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.68
syn-pimaradiene 3-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18937
|
|
|
|
ent-isokauren-2beta-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-isokaurene-2beta,3beta-diol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18938
|
|
|
|
ent-isokaurene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ent-isokaurene-2beta,3beta-diol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18939
|
|
|
|
2alpha-hydroxy-ent-cassadiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-cassa-12,15-dien-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18941
|
|
|
|
ent-cassa-12,15-dien-2-one + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18942
|
|
|
|
ent-cassa-12,15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18943
|
|
|
|
2alpha-hydroxy-ent-cassadiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2alpha-hydroxy-ent-cassadiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18945
|
|
|
|
2alpha-hydroxy-ent-cassadiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18946
|
|
|
|
cucurbitadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-hydroxycucurbitadienol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18953
|
|
|
|
11-hydroxycucurbitadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-oxocucurbitadienol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18954
|
|
|
|
cucurbitadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-oxocucurbitadienol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.71
cucurbitadienol 11-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18955
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 16alpha-hydroxy-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.171
beta-amyrin 16alpha-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-18956
|
|
|
|
drimenol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> drimendiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.72
drimenol monooxygenase
|
–
|
|
|
MetaCyc:
RXN-19012
|
|
|
|
carbon_disulfide + O2 + reduced_[NADPH-hemoprotein_reductase] <=> sulfinylidenemethanethione + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-19031
|
|
|
|
ethanol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1,1-ethanediol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-19034
|
|
|
|
albendazole + O2 + reduced_[NADPH-hemoprotein_reductase] <=> albendazole_S-oxide + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.73
albendazole monooxygenase (sulfoxide-forming)
|
–
|
|
|
MetaCyc:
RXN-19041
|
|
|
|
albendazole + O2 + reduced_[NADPH-hemoprotein_reductase] <=> hydroxyalbendazole + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.74
albendazole monooxygenase (hydroxylating)
|
–
|
|
|
MetaCyc:
RXN-19052
|
|
|
|
febendazole + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4''-hydroxyfenbendazole + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.75
fenbendazole monooxygenase (4'-hydroxylating)
|
–
|
|
|
MetaCyc:
RXN-19053
|
|
|
|
febendazole + O2 + reduced_[NADPH-hemoprotein_reductase] <=> oxfendazole + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.73
albendazole monooxygenase (sulfoxide-forming)
|
–
|
|
|
MetaCyc:
RXN-19054
|
|
|
|
arachidonic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (8Z,11Z,14Z)-5,6-epoxyeicosatrienoic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M19
|
–
|
|
|
MetaCyc:
RXN-19055
|
|
|
|
arachidonic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (5Z,11Z,14Z)-8,9-epoxyeicosatrienoic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M19
|
–
|
|
|
MetaCyc:
RXN-19056
|
|
|
|
arachidonic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (5Z,8Z,14Z)-11,12-epoxyeicosatrienoic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M19
|
–
|
|
|
MetaCyc:
RXN-19057
|
|
|
|
arachidonic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (5Z,8Z,11Z)-14,15-epoxyeicosatrienoic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M19
|
–
|
|
|
MetaCyc:
RXN-19058
|
|
|
|
tryptamine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4-hydroxytryptamine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.99.59
tryptamine 4-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-19089
|
|
|
|
ent-cassa-12,15-diene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19373
|
|
|
|
dolabradiene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 15,16-epoxydolabrene + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.159
dolabradiene monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-19636
|
|
|
|
15,16-epoxydolabrene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3beta-hydroxy-15,16-epoxydolabrene + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.159
dolabradiene monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-19637
|
|
|
|
(S)-beta-macrocarpene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> zealexin_A1 + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.160
zealexin A1 synthase
|
–
|
|
|
MetaCyc:
RXN-19639
|
|
|
|
cis-trans-nepetalactol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 7-deoxyloganetate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
|
|
MetaCyc:
RXN-19643
|
|
|
|
cis-trans-nepetalactol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 7-deoxyloganetic_alcohol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19644
|
|
|
|
flavanone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> a_2-hydroxyflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19645
|
|
|
|
flavanone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> flavone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.76
flavone synthase II
|
–
|
|
|
MetaCyc:
RXN-19646
|
|
|
|
chrysoeriol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3'-O-methyltricetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M29
|
–
|
M
|
|
MetaCyc:
RXN-19652
|
|
|
|
flavone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3''-hydroxyflavone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-19654
|
|
|
|
flavone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5''-hydroxyflavone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M29
|
–
|
|
|
MetaCyc:
RXN-19655
|
|
|
|
liquiritigenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-hydroxyliquiritigenin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.162
flavanone 2-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-19660
|
|
|
|
vitamin_K2 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-hydroxymenaquinone-4 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19673
|
|
|
|
omega-hydroxymenaquinone-4 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-oxomenaquinone-4 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19674
|
|
|
|
omega-oxomenaquinone-4 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-carboxymenaquinone-4 + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19675
|
|
|
|
vitamin_K2 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-carboxymenaquinone-4 + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19676
|
|
|
|
arachidonic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20-hydroxyeicosatetraenoic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-19677
|
|
|
|
omega-hydroxyphylloquinone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-oxophylloquinone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19682
|
|
|
|
omega-oxophylloquinone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oxidized_[NADPH-hemoprotein_reductase] + H2O + omega-carboxyphylloquinone + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19683
|
|
|
|
vitamin_K + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-carboxyphylloquinone + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19684
|
|
|
|
oleanolic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> gypsogenate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-19691
|
|
|
|
arabidiol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 14-apo-arabidiol + oxidized_[NADPH-hemoprotein_reductase] + H2O + (3E)-4,8-dimethylnona-1,3,7-triene
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-19692
|
|
|
|
marneral + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 23-hydroxymarneral + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M30
|
–
|
M
|
|
MetaCyc:
RXN-19693
|
|
|
|
marnerol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 23-hydroxymarnerol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M30
|
–
|
|
|
MetaCyc:
RXN-19694
|
|
|
|
30-hydroxy-beta-amyrin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 30-oxo-beta-amyrin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19712
|
|
|
|
30-oxo-beta-amyrin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 11-deoxoglycyrrhetinic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19713
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-deoxoglycyrrhetinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M32
|
–
|
|
|
MetaCyc:
RXN-19714
|
|
|
|
(+)-trans-abscisic_aldehyde + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 2-trans-(+)-abscisic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19715
|
|
|
|
trans-abscisic_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-trans-abscisic_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19716
|
|
|
|
Abscisic_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> abscisic_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19717
|
|
|
|
abscisic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> abscisic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19718
|
|
|
|
fatty_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> omega-hydroxy_fatty_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M34
|
–
|
|
|
MetaCyc:
RXN-19719
|
|
|
|
Terpendole_E + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Terpendole_B + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-19725
|
|
|
|
stellata-2,6,19-triene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> stellatate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.M35
|
–
|
|
|
MetaCyc:
RXN-19730
|
|
|
|
germacrene_A + O2 + reduced_[NADPH-hemoprotein_reductase] <=> germacra-1(10),4,11(13)-trien-12-oate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.95
germacrene A hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19749
|
|
|
|
levopimaradienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Levopimarate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19784
|
|
|
|
isopimara-7,15-dienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (13S)-pimara-7,15-dien-18-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19785
|
|
|
|
dehydroabietadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dehydroabietate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19786
|
|
|
|
valencene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> beta-nootkatol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19787
|
|
|
|
beta-nootkatol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-nootkatone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19788
|
|
|
|
valencene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-nootkatone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
|
MetaCyc:
RXN-19789
|
|
|
|
a_14alpha-methylsteroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_14alpha-hydroxymethylsteroid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19828
|
|
|
|
a_14alpha-hydroxymethylsteroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_14alpha-formylsteroid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19829
|
|
|
|
a_14alpha-formylsteroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_DELTA14-steroid + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19830
|
|
|
|
obtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 30-hydroxyobtusifoliol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19831
|
|
|
|
30-hydroxyobtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 30-oxoobtusifoliol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19832
|
|
|
|
30-oxoobtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-19833
|
|
|
|
indole-3-acetonitrile + oxidized_[NADPH-hemoprotein_reductase] <=> dehydro(indole-3-yl)acetonitrile + reduced_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19834
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> dehydro(indole-3-yl)acetonitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M36
|
–
|
|
|
MetaCyc:
RXN-19835
|
|
|
|
indole-3-acetonitrile + O2 + reduced_[NADPH-hemoprotein_reductase] <=> hydroxy(1H-indol-3-yl)acetonitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19839
|
|
|
|
Itaconate + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> 2-Hydroxyparaconate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-19903
|
|
|
|
(S)-1-hydroxy-N-methylcanadine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (13S,14R)-1,13-dihydroxy-N-methylcanadine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.163
(S)-1-hydroxy-N-methylcanadine 13-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-19906
|
|
|
|
19E-geissoschizine + H+ + O2 + reduced_[NADPH-hemoprotein_reductase] <=> intermediate_I + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.M23
|
–
|
M
|
|
MetaCyc:
RXN-19985
|
|
|
|
Vomilenine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> perakine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.104
vinorine hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-19991
|
|
|
|
fraxetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> sideretin_(reduced_form) + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.164
fraxetin 5-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-20026
|
|
|
|
8-methoxypsoralen + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5-hydroxyxanthotoxin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.164
fraxetin 5-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-20028
|
|
|
|
indole-3-carbonyl_nitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4-hydroxyindole-3-carbonyl_nitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.165
indole-3-carbonyl nitrile 4-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-20040
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> hydroxy(1H-indol-3-yl)acetonitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M40
|
–
|
|
|
MetaCyc:
RXN-20041
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20049
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_[NADPH-hemoprotein_reductase] + O2 + H+ <=> 8-epi-inunolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.170
8-epi-inunolide synthase
|
–
|
|
|
MetaCyc:
RXN-20051
|
|
|
|
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6alpha,8beta-dihydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20052
|
|
|
|
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced_[NADPH-hemoprotein_reductase] + O2 + H+ <=> eupatolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.169
eupatolide synthase
|
–
|
|
|
MetaCyc:
RXN-20054
|
|
|
|
benzoyl-CoA + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 2-hydroxybenzoyl-CoA + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-2008
|
|
|
|
(S)-tetrahydropalmatrubine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> dihydroberbine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-20167
|
|
|
|
melissoate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 30-hydroxytriacontanoate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.fr
|
–
|
M
|
|
MetaCyc:
RXN-20353
|
|
|
|
ultra-long-chain_fatty_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ultra-long-chain_omega-hydroxy_fatty_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.fr
|
–
|
|
|
MetaCyc:
RXN-20389
|
|
|
|
4alpha,14alpha-dimethyl-cholesta-8-enol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-cholesta-8,14-dienol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-20438
|
|
|
|
4alpha,_14alpha-dimethyl_ergosta-8,25(27)-dienol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl_ergosta-8,14,25(27)-trienol + formate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
M
|
|
MetaCyc:
RXN-20445
|
|
|
|
parathion + O2 + reduced_[NADPH-hemoprotein_reductase] <=> paraoxon + H2O + Sulfide + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20736
|
|
|
|
L-leucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (E/Z)-isovaleraldoxime + oxidized_[NADPH-hemoprotein_reductase] + CO2 + H2O
|
1.14.14.M43
|
–
|
|
|
MetaCyc:
RXN-20853
|
|
|
|
isovaleronitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (2R)-2-hydroxy-3-methylbutanenitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20856
|
|
|
|
isovaleronitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3-hydroxy-3-methylbutanenitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20858
|
|
|
|
3-methyl-2-butenenitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (Z)-4-hydroxy-3-methylbut-2-enenitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20860
|
|
|
|
isovaleronitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-4-hydroxy-3-methylbutanenitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20862
|
|
|
|
(Z)-4-hydroxy-3-methylbut-2-enenitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4-hydroxy-3-(hydroxymethyl)-2-butenenitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20865
|
|
|
|
N-geranyl-L-glutamate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-(7''-carboxy-7''-demethylgeranyl)-L-glutamate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-20870
|
|
|
|
N-geranyl-L-glutamate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-(7''-hydroxylgeranyl)-L-glutamate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-20902
|
|
|
|
N-(7''-hydroxylgeranyl)-L-glutamate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-(7''-oxolgeranyl)-L-glutamate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-20903
|
|
|
|
N-(7''-oxolgeranyl)-L-glutamate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-(7''-carboxy-7''-demethylgeranyl)-L-glutamate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-20904
|
|
|
|
L-leucine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-leucine + oxidized_[NADPH-hemoprotein_reductase] + H+ + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20907
|
|
|
|
N-hydroxy-L-leucine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxy-L-leucine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20908
|
|
|
|
(E/Z)-isovaleraldoxime + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (2R)-2-hydroxy-3-methylbutanenitrile + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M44
|
–
|
|
|
MetaCyc:
RXN-20910
|
|
|
|
(E/Z)-isovaleraldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4-hydroxy-3-(hydroxymethyl)-2-butenenitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M44
|
–
|
|
|
MetaCyc:
RXN-20911
|
|
|
|
(E/Z)-isovaleraldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (S)-4-hydroxy-3-methylbutanenitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.M44
|
–
|
|
|
MetaCyc:
RXN-20912
|
|
|
|
5beta-Pregnan-3beta-ol-20-one + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5beta-pregnane-3beta,14beta-diol-20-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-20955
|
|
|
|
5beta-pregnane-3beta,14beta-diol-20-one + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3beta,14beta,21-trihydroxy-5beta-pregnane-20-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-20956
|
|
|
|
digitoxin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> digoxin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M45
|
–
|
M
|
|
MetaCyc:
RXN-20961
|
|
|
|
digitoxigenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> gitoxigenin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M47
|
–
|
M
|
|
MetaCyc:
RXN-20962
|
|
|
|
purpurea_glycoside_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> deacetyl-lanatoside_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M45
|
–
|
M
|
|
MetaCyc:
RXN-20969
|
|
|
|
lanatoside_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> lanatoside_C + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M45
|
–
|
M
|
|
MetaCyc:
RXN-20972
|
|
|
|
digitoxin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> gitoxin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M46
|
–
|
|
|
MetaCyc:
RXN-20973
|
|
|
|
purpurea_glycoside_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> purpurea_glycoside_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M46
|
–
|
|
|
MetaCyc:
RXN-20975
|
|
|
|
(6E)-nerolidol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (6E)-9-hydroxynerolidol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-21054
|
|
|
|
Zymosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-hydroxymethyl-14alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21165
|
|
|
|
4alpha-hydroxymethyl-14alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-formyl-14alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21166
|
|
|
|
4alpha-formyl-14alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21167
|
|
|
|
4alpha,14alpha-dimethyl-cholesta-8-enol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-hydroxymethyl-14alpha-methyl-cholesta-8-enol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21168
|
|
|
|
4alpha-hydroxymethyl-14alpha-methyl-cholesta-8-enol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-formyl-14alpha-methyl-cholesta-8-enol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21169
|
|
|
|
4alpha-formyl-14alpha-methyl-cholesta-8-enol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-cholesta-8,14-dienol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21170
|
|
|
|
ferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> pisiferol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21384
|
|
|
|
ferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> pisiferic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.61
carnosic acid synthase
|
–
|
|
|
MetaCyc:
RXN-21385
|
|
|
|
miltiradiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 11-oxomiltiradiene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-21386
|
|
|
|
pisiferol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 20-oxoferruginol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21387
|
|
|
|
20-oxoferruginol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> pisiferic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21388
|
|
|
|
tricholomate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Ibotenate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-21516
|
|
|
|
16-deoxyversicolorin_A + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 16-deoxyversicolorin_A_epoxide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-21581
|
|
|
|
glucobrassicin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4-hydroxyglucobrassicin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13.M51
|
–
|
M
|
|
MetaCyc:
RXN-2162
|
|
|
|
L-homomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (E)-4-(methylsulfanyl)butanal_oxime + CO2 + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-2206
|
|
|
|
4-coumaroylshikimate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> trans-5-O-caffeoylshikimate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-2581
|
|
|
|
liquiritigenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2'-hydroxydihydrodaidzein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
M
|
|
MetaCyc:
RXN-3283
|
|
|
|
Biochanin_A + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Pratensein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.88
isoflavone 3'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-3761
|
|
|
|
formononetin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Calycosin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.88
isoflavone 3'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-3762
|
|
|
|
Calycosin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> pseudobaptigenin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.63
pseudobaptigenin synthase
|
–
|
M
|
|
MetaCyc:
RXN-3763
|
|
|
|
pseudobaptigenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2''-hydroxypseudobaptigenin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-3765
|
|
|
|
campesterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (22S)-22-hydroxycampesterol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4225
|
|
|
|
5alpha-campestan-3-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4230
|
|
|
|
(24R)-ergost-4-en-3-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4231
|
|
|
|
6-deoxotyphasterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-hydroxytyphasterol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4241
|
|
|
|
sitosterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> stigmasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.41
sterol 22-desaturase
|
–
|
M
|
|
MetaCyc:
RXN-4243
|
|
|
|
N6-(Delta2-isopentenyl)-adenosine_5''-triphosphate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ATP + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4304
|
|
|
|
N6-(Delta2-isopentenyl)-adenosine_5''-diphosphate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ADP + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4306
|
|
|
|
N6-(Delta2-isopentenyl)-adenosine_5''-monophosphate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N6-(4-hydroxy-3-methyl-2-(E)-butyl)adenosine_5'-phosphate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4308
|
|
|
|
1,8-cineole + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-exo-hydroxy-1,8-cineole + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.56
1,8-cineole 2-exo-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-4342
|
|
|
|
a_long-chain_alkane + O2 + reduced_[NADPH-hemoprotein_reductase] <=> long-chain_fatty_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4443
|
|
|
|
daidzein + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2''-hydroxydaidzein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-4501
|
|
|
|
demethylmedicarpin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (6aS,11aS)-3,6a,9-trihydroxypterocarpan + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.93
3,9-dihydroxypterocarpan 6a-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-4505
|
|
|
|
2-(or_4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + reduced_[NADPH-hemoprotein_reductase] + O2 <=> glyceollin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.135
glyceollin synthase
|
–
|
M
|
|
MetaCyc:
RXN-4511
|
|
|
|
(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced_[NADPH-hemoprotein_reductase] + O2 <=> glyceollin_II + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.135
glyceollin synthase
|
–
|
M
|
|
MetaCyc:
RXN-4512
|
|
|
|
(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced_[NADPH-hemoprotein_reductase] + O2 <=> glyceollin_III + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.135
glyceollin synthase
|
–
|
M
|
|
MetaCyc:
RXN-4513
|
|
|
|
7-deoxyloganate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> loganic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-4521
|
|
|
|
loganic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> H2O + secologanate + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.62
secologanin synthase
|
–
|
|
|
MetaCyc:
RXN-4522
|
|
|
|
(+)-maackiain + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-6a-hydroxymaackiain + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-4561
|
|
|
|
L-phenylalanine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (E)-phenylacetaldoxime + oxidized_[NADPH-hemoprotein_reductase] + H2O + CO2
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-4602
|
|
|
|
5-epiaristolochene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1beta-hydroxy-5-epiaristolochene + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-4801
|
|
|
|
5-epiaristolochene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1-deoxycapsidiol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-4802
|
|
|
|
1beta-hydroxy-5-epiaristolochene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> capsidiol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-4803
|
|
|
|
1-deoxycapsidiol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> capsidiol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-4804
|
|
|
|
(-)-vetispiradiene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> solavetivol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-4842
|
|
|
|
L-valine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-valine + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-5063
|
|
|
|
N-hydroxy-L-valine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxy-L-valine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-5064
|
|
|
|
Isobutyronitrile + O2 + reduced_[NADPH-hemoprotein_reductase] <=> acetone_cyanohydrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-5082
|
|
|
|
ent-kaur-16-en-19-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-kaur-16-en-19-al + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-5242
|
|
|
|
(+)-dihydrokaempferol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> taxifolin + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-525
|
|
|
|
zeinoxanthin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> lutein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-5962
|
|
|
|
gibberellin_A12_aldehyde + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Gibberellin_A14_aldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-6545
|
|
|
|
Gibberellin_A14_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Gibberellin_A14 + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-6549
|
|
|
|
indole + O2 + reduced_[NADPH-hemoprotein_reductase] <=> indolin-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.153
indole-2-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-6681
|
|
|
|
indolin-2-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3-hydroxyindolin-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.157
indolin-2-one monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-6682
|
|
|
|
3-hydroxyindolin-2-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.109
3-hydroxyindolin-2-one monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-6683
|
|
|
|
2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.110
2-hydroxy-1,4-benzoxazin-3-one monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-6684
|
|
|
|
genistein + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2''-hydroxygenistein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-7141
|
|
|
|
6-Oxocampestanol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Cathasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-715
|
|
|
|
Cathasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Teasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-716
|
|
|
|
typhasterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 24-epicastasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-719
|
|
|
|
24-epicastasterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 24-epibrassinolide + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-720
|
|
|
|
ent-kaur-16-en-19-al + reduced_[NADPH-hemoprotein_reductase] + O2 <=> ent-kaur-16-en-19-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-7580
|
|
|
|
Gibberellin_A14 + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> gibberellin_a4 + CO2 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7619
|
|
|
|
gibberellin_GA7 + O2 + reduced_[NADPH-hemoprotein_reductase] <=> gibberellin + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7621
|
|
|
|
gibberellin_A12 + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> gibberellin_a9 + CO2 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7624
|
|
|
|
4-coumaroyl-4''-hydroxyphenyllactate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> caffeoyl-4''-hydroxyphenyllactate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7628
|
|
|
|
caffeoyl-4''-hydroxyphenyllactate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> rosmarinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7629
|
|
|
|
4-coumaroyl-4''-hydroxyphenyllactate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4-coumaroyl-3,4''-dihydroxyphenyllactate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7630
|
|
|
|
4-coumaroyl-3,4''-dihydroxyphenyllactate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> rosmarinic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7631
|
|
|
|
naringenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> apigenin + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.19.76
flavone synthase II
|
–
|
M
|
|
MetaCyc:
RXN-7650
|
|
|
|
naringenin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> eriodictyol + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-7652
|
|
|
|
eriodictyol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> luteolin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.76
flavone synthase II
|
–
|
M
|
|
MetaCyc:
RXN-7653
|
|
|
|
liquiritigenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6,7,4''-trihydroxyflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7654
|
|
|
|
6,7,4''-trihydroxyflavanone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2,6,7,4''-tetrahydroxyisoflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-7655
|
|
|
|
campesterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-deoxocathasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-773
|
|
|
|
6-deoxocathasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-deoxoteasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-774
|
|
|
|
N-hydroxy-L-tyrosine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N,N-dihydroxy-L-tyrosine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-7748
|
|
|
|
apigenin + reduced_[NADPH-hemoprotein_reductase] + H+ + O2 <=> 2,5,7,4'-tetrahydroxyisoflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
M
|
|
MetaCyc:
RXN-7750
|
|
|
|
6-deoxotyphasterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6-Deoxocastasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-777
|
|
|
|
6-Deoxocastasterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 6alpha-Hydroxy-castasterone + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-778
|
|
|
|
(+)-dihydrokaempferol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> dihydromyricetin + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-7782
|
|
|
|
flavanone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 3''-hydroxy_flavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-7783
|
|
|
|
6alpha-Hydroxy-castasterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 24-epicastasterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-779
|
|
|
|
sitosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (22alpha)-hydroxy-sitosterol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-7876
|
|
|
|
isofucosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (22alpha)-hydroxy-isofucosterol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-7877
|
|
|
|
5alpha-cholestanol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (22alpha)-hydroxy-cholestanol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-7878
|
|
|
|
eriodictyol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (2S)-dihydrotricetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-7921
|
|
|
|
taurochenodeoxycholate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> taurohyocholate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-7976
|
|
|
|
lithocholic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> hyodeoxycholic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-7977
|
|
|
|
25-hydroxycholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7alpha,25-Dihydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-7980
|
|
|
|
27-Hydroxycholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (25R)-cholest-5-ene-3beta,7alpha,26-triol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-7981
|
|
|
|
isoliquiritigenin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> butein + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-8009
|
|
|
|
amorpha-4,11-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinic_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8050
|
|
|
|
artemisinic_alcohol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinic_aldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8051
|
|
|
|
(11R)-dihydroartemisinic_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dihydroartemisinate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8055
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 24-hydroxy-beta-amyrin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-8082
|
|
|
|
beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> sophoradiol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M31
|
–
|
M
|
|
MetaCyc:
RXN-8083
|
|
|
|
sophoradiol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> soyasapogenol_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-8084
|
|
|
|
24-hydroxy-beta-amyrin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> soyasapogenol_B + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.M31
|
–
|
M
|
|
MetaCyc:
RXN-8085
|
|
|
|
(S)-reticuline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 1,2-dehydroreticuline + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.54
1,2-dehydroreticuline synthase
|
–
|
M
|
|
MetaCyc:
RXN-8142
|
|
|
|
(S)-cis-N-Methylstylopine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> protopine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-8180
|
|
|
|
geraniol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (6E)-8-hydroxygeraniol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.83
geraniol 8-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-8197
|
|
|
|
19E-geissoschizine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> polyneuridine_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.M24
|
–
|
M
|
|
MetaCyc:
RXN-8224
|
|
|
|
Nicotine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-nornicotine + oxidized_[NADPH-hemoprotein_reductase] + H2O + formaldehyde
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-8248
|
|
|
|
(R)-dihydrocamalexate + reduced_[NADPH-hemoprotein_reductase] + O2 + H+ <=> camalexin + CO2 + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8275
|
|
|
|
ergosta-5-enol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> brassicasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.41
sterol 22-desaturase
|
–
|
M
|
|
MetaCyc:
RXN-8352
|
|
|
|
demethylsuberosin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (+)-marmesin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.66
marmesin synthase
|
–
|
M
|
|
MetaCyc:
RXN-8383
|
|
|
|
(+)-marmesin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> psoralen + oxidized_[NADPH-hemoprotein_reductase] + acetone + H2O
|
1.14.14.141
psoralen synthase
|
–
|
M
|
|
MetaCyc:
RXN-8386
|
|
|
|
abieta-7,13-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> abietadienol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.144
abieta-7,13-diene hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-8507
|
|
|
|
abietadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> abieta-7,13-dien-18,18-diol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8508
|
|
|
|
abietadienal + reduced_[NADPH-hemoprotein_reductase] + O2 <=> abietic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8510
|
|
|
|
levopimaradienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> levopiramadiene-diol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8517
|
|
|
|
levopimaradienal + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Levopimarate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8518
|
|
|
|
dehydroabietadienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dehydroabietadiene-diol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8532
|
|
|
|
dehydroabietadienal + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dehydroabietate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8534
|
|
|
|
isopimara-7,15-dienol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> isopimaradiene-diol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-8536
|
|
|
|
isopimaradienal + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (13S)-pimara-7,15-dien-18-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8538
|
|
|
|
(E,E)-geranyllinalool + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (E,E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene + 3-buten-2-one + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.58
trimethyltridecatetraene synthase
|
–
|
M
|
|
MetaCyc:
RXN-8620
|
|
|
|
acetone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Hydroxyacetone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-8630
|
|
|
|
3''-hydroxy_flavanone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3,5''-dihydroxy_isoflavanone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-8671
|
|
|
|
(+)-pinoresinol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (+)-piperitol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.74
(+)-piperitol/(+)-sesamin synthase
|
–
|
M
|
|
MetaCyc:
RXN-8695
|
|
|
|
(+)-piperitol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> sesamin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.74
(+)-piperitol/(+)-sesamin synthase
|
–
|
M
|
|
MetaCyc:
RXN-8696
|
|
|
|
(R)-N-methylcoclaurine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (R,R)-guattegaumerine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-8702
|
|
|
|
tryptamine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> serotonin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-8707
|
|
|
|
(-)-deoxypodophyllotoxin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> beta-peltatin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-8735
|
|
|
|
(-)-deoxypodophyllotoxin + O2 + reduced_[NADPH-hemoprotein_reductase] <=> Epipodophyllotoxins + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.132
(-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-8737
|
|
|
|
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl_acetate + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13.146
taxoid 14beta-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-8855
|
|
|
|
4-hydroxybenzaldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3,4-Dihydroxybenzaldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-8872
|
|
|
|
geranylhydroquinone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 3''''-hydroxy-geranylhydroquinone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.174
geranylhydroquinone 3''-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-8922
|
|
|
|
germacrene_A + O2 + reduced_[NADPH-hemoprotein_reductase] <=> germacra-1(10),4,11(13)-trien-12-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8962
|
|
|
|
germacra-1(10),4,11(13)-trien-12-ol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> germacra-1(10),4,11(13)-trien-12-al + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8969
|
|
|
|
germacra-1(10),4,11(13)-trien-12-al + O2 + reduced_[NADPH-hemoprotein_reductase] <=> germacra-1(10),4,11(13)-trien-12-oate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8970
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> (+)-costunolide + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.150
costunolide synthase
|
–
|
|
|
MetaCyc:
RXN-8971
|
|
|
|
(+)-delta-Cadinene + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 8-hydroxy-(+)-delta-cadinene + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-9045
|
|
|
|
(S)-Autumnaline + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Isoandrocymbine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-9206
|
|
|
|
(S)-reticuline + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (S)-corytuberine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
M
|
|
MetaCyc:
RXN-9314
|
|
|
|
7-deoxyloganetic_alcohol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> iridotrial + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-9371
|
|
|
|
(1''S)-averantin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (1''S,5''S)-hydroxyaverantin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-9481
|
|
|
|
(1''S)-averantin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (1''S,5''R)-hydroxyaverantin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-9482
|
|
|
|
(1''S,5''S)-averufin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 1'-hydroxyversicolorone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-9486
|
|
|
|
8-O-methylsterigmatocystin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> aflatoxin_B1 + oxidized_[NADPH-hemoprotein_reductase] + H2O + CO2 + methanol
|
1.14.14.117
aflatoxin B synthase
|
–
|
M
|
|
MetaCyc:
RXN-9497
|
|
|
|
8-O-methyldihydrosterigmatocystin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Aflatoxin_B2 + oxidized_[NADPH-hemoprotein_reductase] + H2O + CO2 + methanol
|
1.14.14.117
aflatoxin B synthase
|
–
|
M
|
|
MetaCyc:
RXN-9502
|
|
|
|
thalianol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 7beta-hydroxythalianol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-9631
|
|
|
|
L-isoleucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N-hydroxy-L-isoleucine + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-9636
|
|
|
|
7beta-hydroxythalianol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> desaturated_7beta-hydroxythalianol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-9637
|
|
|
|
N-hydroxy-L-isoleucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N,N-dihydroxy-L-isoleucine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-9638
|
|
|
|
(2S)-methylbutanenitrile + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-Methyl-2-hydroxybutyronitrile + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-9642
|
|
|
|
(+)-columbianetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> angelicin + acetone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.148
angelicin synthase
|
–
|
|
|
MetaCyc:
RXN-9689
|
|
|
|
trans-9,10-epoxystearate + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 18-hydroxy-9(10)-epoxystearic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-9805
|
|
|
|
9,10-dihydroxystearic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 9,10,18-trihydroxyoctadecanoic_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.80
long-chain fatty acid omega-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-9807
|
|
|
|
vitamin_D3 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 25-hydroxyvitamin_D3 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
M
|
|
MetaCyc:
RXN-9829
|
|
|
|
cholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (22R)-22-hydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13
|
–
|
M
|
|
MetaCyc:
RXN18C3-235
|
|
|
|
(22R)-22-hydroxycholesterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 22,26-dihydroxycholesterol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.13
|
–
|
M
|
|
MetaCyc:
RXN18C3-3
|
|
|
|
furostanol-26-alcohol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> furostanol-26-aldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN18C3-5
|
|
|
|
gibberellin_A12 + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Gibberellin_A53 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN1F-143
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_[NADPH-hemoprotein_reductase] + O2 <=> gibberellin_A12_aldehyde + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN1F-160
|
|
|
|
gibberellin_A12_aldehyde + reduced_[NADPH-hemoprotein_reductase] + O2 <=> gibberellin_A12 + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN1F-161
|
|
|
|
gibberellin_a4 + O2 + reduced_[NADPH-hemoprotein_reductase] <=> gibberellin_1 + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN1F-166
|
|
|
|
lanosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN3O-130
|
|
|
|
5-dehydroepisterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.19.41
sterol 22-desaturase
|
–
|
M
|
|
MetaCyc:
RXN3O-227
|
|
|
|
Abscisic_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> abscisic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN4FS-22
|
|
|
|
trans-abscisic_alcohol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2-trans-(+)-abscisic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN4FS-23
|
|
|
|
24,25-dihydrolanosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 8-lanostene-3beta,32-diol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-11
|
|
|
|
8-lanostene-3beta,32-diol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8-en-3beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-12
|
|
|
|
4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8-en-3beta-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-13
|
|
|
|
Nicotine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 2''-hydroxynicotine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-146
|
|
|
|
cotinine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> trans-3''-hydroxycotinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-161
|
|
|
|
cotinine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5''-hydroxycotinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-163
|
|
|
|
cotinine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N''-hydroxymethyl-norcotinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-169
|
|
|
|
bupropion + reduced_[NADPH-hemoprotein_reductase] + O2 <=> hydroxybupropion + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-181
|
|
|
|
ethanol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> acetaldehyde + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN66-2
|
|
|
|
lanosterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> hydroxylanosterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-303
|
|
|
|
hydroxylanosterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> oxolanosterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-304
|
|
|
|
oxolanosterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-305
|
|
|
|
pregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 17alpha-hydroxypregnenolone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-340
|
|
|
|
17alpha-hydroxypregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> dehydroepiandrosterone + acetate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
M
|
|
MetaCyc:
RXN66-341
|
|
|
|
4-androstene-3,17-dione + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 19-hydroxyandrost-4-ene-3,17-dione + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-344
|
|
|
|
19-hydroxyandrost-4-ene-3,17-dione + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 19-oxoandrost-4-ene-3,17-dione + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-345
|
|
|
|
19-oxoandrost-4-ene-3,17-dione + reduced_[NADPH-hemoprotein_reductase] + O2 <=> estrone + formate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-346
|
|
|
|
testosterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 19-hydroxytestosterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-347
|
|
|
|
19-hydroxytestosterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 19-oxotestosterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-348
|
|
|
|
19-oxotestosterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 17beta-estradiol + H2O + formate + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN66-349
|
|
|
|
progesterone + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 17alpha-hydroxyprogesterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-355
|
|
|
|
apigenin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> luteolin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN66-587
|
|
|
|
tamarixetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> quercetin + oxidized_[NADPH-hemoprotein_reductase] + formaldehyde + H2O + H+
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-589
|
|
|
|
testosterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 6beta-hydroxytestosterone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-591
|
|
|
|
galangin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> kaempferol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-595
|
|
|
|
kaempferide + reduced_[NADPH-hemoprotein_reductase] + O2 <=> kaempferol + oxidized_[NADPH-hemoprotein_reductase] + formaldehyde + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-596
|
|
|
|
Phenacetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> acetaminophen + oxidized_[NADPH-hemoprotein_reductase] + acetaldehyde + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-597
|
|
|
|
Caffeine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> paraxanthine + oxidized_[NADPH-hemoprotein_reductase] + formaldehyde + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-598
|
|
|
|
diclofenac + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 4''-hydroxydiclofenac + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-599
|
|
|
|
amphetamine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> alpha-methyltyramine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-600
|
|
|
|
Nicotine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> nicotine-Delta1''5''-iminium_ion + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN66-61
|
|
|
|
L-dihomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (E)-5-(methylsulfanyl)pentanal_oxime + H2O + CO2 + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXNQT-4309
|
|
|
|
L-trihomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> H2O + CO2 + oxidized_[NADPH-hemoprotein_reductase] + 6-Methylthiohexanaldoxime
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXNQT-4310
|
|
|
|
L-tetrahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> H2O + CO2 + oxidized_[NADPH-hemoprotein_reductase] + 4-methylthioheptanaldoxime
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXNQT-4311
|
|
|
|
L-pentahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4-methylthiooctanaldoxime + CO2 + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXNQT-4312
|
|
|
|
L-hexahomomethionine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> H2O + CO2 + oxidized_[NADPH-hemoprotein_reductase] + 4-methylthiononanaldoxime
|
1.14.14.42
homomethionine N-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXNQT-4313
|
|
|
|
squalene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.17
squalene monooxygenase
|
–
|
M
|
|
MetaCyc:
SQUALENE-MONOOXYGENASE-RXN
|
|
|
|
a_C21_steroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_17alpha-hydroxy-C21-steroid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
|
|
MetaCyc:
STEROID-17-ALPHA-MONOOXYGENASE-RXN
|
|
|
|
a_C21_steroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 21-hydroxy-C21-steroid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
|
|
MetaCyc:
STEROID-21-MONOOXYGENASE-RXN
|
|
|
|
Cinnamic_acid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> p-coumaric_acid + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
M
|
|
MetaCyc:
TRANS-CINNAMATE-4-MONOOXYGENASE-RXN
|
|
|
|
L-tyrosine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-tyrosine + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
TYROSINE-N-MONOOXYGENASE-RXN
|
|
|
|
organic_molecule + reduced_[NADPH-hemoprotein_reductase] + O2 <=> an_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
UNSPECIFIC-MONOOXYGENASE-RXN
|
|